Docente
Ana Sofia Da Fonseca Ramos

Resume

Ana Sofia Fonseca Ramos holds a degree in Biotechnology Engineering (2003), an MSc in Biotechnology Engineering (2011), and a PhD in Health Sciences (2025). She has completed multiple hands-on training programs in bioinformatics and computational biology, including pharmaceutical bioinformatics, artificial intelligence in drug discovery, next-generation sequencing (NGS) analysis, bulk RNA-seq, network and pathway analysis, and metagenomics (Qiime2). With a strong background in cancer research and bioinformatics, Ana Sofia has published three articles in peer-reviewed international journals, presented at 11 scientific events, and supervised two undergraduate theses, co-supervised three BSc projects, and one MSc thesis. Since 2021, she has been an Assistant Professor at Universidade Lusófona, where she teaches Human Genetics, Immunology, and Bioinformatics. Her research focuses on identifying diagnostic and prognostic biomarkers in cancer, investigating tumor microenvironment progression-related mechanisms, and discovering novel inhibitors. More recently, she has expanded her interests to inflammatory mechanisms and their role in disease progression.

Graus

• Licenciatura
  Biotechnology engineering
• Mestrado
  Biotechnology Engineering
• Pós-Graduação
  MBA em Gestão de Empresas
• Doktor (PhD)
  Health Sciences
• Outros
  Training in Clinical Trial Monitoring
• DESE
  Data Science com Python
• Outros
  Molecular Bioinformatics Online Practical Course
• Outros
  Next Generation Sequencing Analysis
• Diplôme d´études supérieures
  MOOC Machine Learning y Big Data para la Bioinformática
• Outros
  Pharmaceutical Bionformatics
• Outros
  Applied Pharmaceutical Bioinformatics
• Outros
  Applied Pharmaceutical Structural Bioinformatics
• Outros
  Artificial Intelligence in Drug Discovery
• Outros
  Epigenetics - Foundations
• Outros
  Epigenetics - Human Health
• Outros
  The 7th Evidence-Based Research Training School
• Outros
  Drug discovery and Development
• Outros
  Genomes, Networks and Pathways
• Outros
  Cancer Genomics
• Outros
  NGS - Sequence to insights
• Outros
  DMSL Python
• Outros
  Workshop on RNASeq data analysis using R
• Outros
  Mini-course - Metagenomics: from basics to applications

Publicações

Journal article

• 2025-05, Interaction between redox regulation, immune activation, and response to treatment in HER2+ breast cancer, Redox Biology
• 2023-09-05, Lysyl oxidase like 2: an enzyme at the crossroad of Toxicology and Pharmacology, Toxicology Letters
• 2022-06-21, Lysyl Oxidases Expression and Breast Cancer Progression: A Bioinformatic Analysis, Frontiers in Pharmacology
• 2020-12, Gene expression and survival analysis in cancer research using online open access platforms: a comparative analysis, Biomedical and Biopharmaceutical Research Journal

Conference abstract

• 2023-11-30, LusoModLox: in search of therapeutic lysyl oxidase inhibitors, CBIOS Conference
• 2023-02-01, A Novel Lysyl Oxidase Like 2 Inhibitor decreases Breast Cancer cells migration, 53rd Meeting of the Portuguese Society of Pharmacology, 41st Meeting of Clinical Pharmacology and 22nd Meeting of Toxicology
• 2023, Synchronized expression dysregulation of Redox and Calcium-related genes: implications for breast cancer patient survival. , 5th CBIOS conference
• 2022-07-14, Simultaneous expression dysregulation of redox and calcium signalling-related genes: impact on breast cancer patient survival, FEBS
• 2022-07-14, Lysyl oxidase like 2 as a therapeutic target for breast cancer: bioinformatics analysis and biochemical evaluation of 4-thiazolidinone derivatives, FEBS
• 2021-10-17, Lysyl Oxidases in the pathophysiology of breast cancer: a bioinformatics approach., Biomed Biopharm Res
• 2021-10-06, Bioinformatics analysis for Lysyl Oxidases as therapeutic targets for breast cancer, Molecular Analysis for Precision Oncology Congress 2021

Conference poster

• 2024-02, Coordinated Expression of Genes Related to Redox status and Ca2+ homeostasis: Implications for Breast Cancer Patient Survival., EACR Virtual Conference on Signaling Circuits in Cancer
• 2023-11-28, Crosstalk between Expression of Redox and Calcium Signaling Genes and Its Impact on Breast Cancer Patient Survival.RSGDREAM 2023, RECOMB/ISCB Conference on Regulatory & Systems Genomics with DREAM Challenges (RSGDREAM) 2023
• 2023-11-25, Exploring the Multifaceted Potential of EPCU in Targeting Tumorigenesis and Hormone Regulation, 2nd Asian Council Symposium
• 2023-07-05, The influence of Redox and Calcium signalling-related gene expression profiles on the progression of Breast Cancer, Encontro de Ciencia 2023
• 2022-07-14, Lysyl oxidase like 2 as a therapeutic target for breast cancer: bioinformatics analysis and biochemical evaluation of 4-thiazolidinone derivatives, The Biochemistry Global Summit, Lisbon 2022
• 2022-07-14, Expression profile of cellular redox and calcium signalling-related genes: role in breast cancer progression., The Biochemistry Global Summit, Lisbon 2022
• 2022-07, Targeting lysyl oxidases for breast cancertherapy: bioinformatic analysis and evaluationof 4-thiazolidinone derivatives as LOXL2inhibitors, The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress
• 2022, NiPharmins as efficacious prophylactic options to prevent Staphylococcal infections, 3rd INSA's Young Researcher Day, Lisbon, Portugal, 8 November
• 2022, Bioinformatic analysis of Claudin genes family as therapeutic targets for pancreatic adenocarcinoma, ISCB-Latin America SolBio BioNetMX Conference on Bioinformatics 2022, Juriquilla, Mexico, 3-7 November
• 2021-10-14, Lysyl Oxidases in the pathophysiology of breast cancer: a bioinformatics approach, 56º Congresso Anual da SBFIS Online
• 2021-10-07, Bioinformatics analysis for Lysyl Oxidases as therapeutic targets for breast cancer., Molecular Analysis for Precision Oncology Virtual Congress 2021
• 2021-09-24, Lisil Oxidases como possíveis alvos terapêuticos para o cancro da mama: análise baseada na bioinformática., 3º Encontro Nacional de Jovens Investigadores em Oncologia. Congresso Híbrido.
• 2020-10-08, Bioinformatic Databases as a tool to analyze alterations in Cell Physiology in Carcinogenesis: A comparative analysis of open access data analysis platforms., Fisiologia ainda sob estresse em tempos da COVID-19

Other output

• 2022, Human Genetics - Oncobiology (didactic material)