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Class Pharmacology I

  • Presentation

    Presentation

    Pharmacology constitutes a fundamental CU for the knowledge of drugs, especially regarding their mechanisms of action, pharmacological effects and their characteristics in terms of molecular and biological interactions. This curricular unit (CU) is thus crucial in a graduation in pharmaceutical sciences.
  • Code

    Code

    ULHT477-3581
  • Syllabus

    Syllabus

    Introduction to Pharmacology: Historical perspective Introduction to Pharmacology: basic concepts Sources of information related with medicines Research methodologies in experimental pharmacology The life-cycle of medicines Pharmacokinetics and Pharmacodynamics: Drug delivery routes Pharmacokinetics: Absorption, distribution, metabolism and excretion of drugs General mechanisms of drug action: theory of receivers; Dose-response curves Drugs that act on the nervous system: Parasympathomimetics and antimuscarinics Sympathomimetics and adrenergic antagonists Neuromuscular junction blockers Anxiolytics, sedatives and hypnotics Antidepressants Psychostimulants Antipsychotics Antiepileptics General and local anesthetics Opioids Antiparkinsonics  Drugs used in Alzheimer disease
  • Objectives

    Objectives

    Demonstrate knowledge on the terminology and basic concepts of Pharmacology Understand the steps of medicines life-cycle Understand the administration routes and pharmacokinetic processes and their influence on therapeutics Understand the pharmacodynamic processes, describing the main mechanisms of drug action Demonstrate general knowledge on the research methodologies of Pharmacology. Use specialized sources of information in the field of medicines Understand the mechanisms of action and therapeutic uses of the main drug classes that act in central and peripheral nervous system, identifying the most representative drugs and knowing the most relevant adverse effects and interactions The CU will also contribute to the development of transversal competences such as the ability to work in groups, the critical spirit, the ability to explain and communicate scientific topics, and the technical skills associated with laboratory work.
  • Teaching methodologies and assessment

    Teaching methodologies and assessment

    In Pharmacology I, innovative learning tools are used, such as group games in the classroom, interactive online games (individual and group) on the various topics covered in class, in order to increase student interest and learning.
  • References

    References

    Guimarães, S., Moura, D., Soares da Silva, P. (2014). Terapêutica Medicamentosa e suas bases Farmacológicas. Porto: Porto Editora.  Goodman, L.S.. (2018). Goodman & Gilman's. As Bases Farmacológicas da Terapêutica (13ª Ed.) New York, NY: McGraw Hill.  Katzung, B. G.. (2018). Basic and Clinical Pharmacology (14th Ed). San Francisco, CA: McGraw-Hill.
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