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Presentation
Presentation
Immunology, in addition to being a basic discipline in university education in Health courses, is central to Pharmaceutical Sciences. To understand the development and performance of vaccines, immunomodulatory drugs and immunotherapies, it is necessary for students to understand the fundamentals of the immune response and the pathologies resulting from its dysfunction. This course allows students to develop practical and analytical skills, which are very useful in the job market, master's and doctoral courses, chemical-pharmaceutical research, pathology and diagnostic laboratories, clinical trials, among others. In addition, obtaining, using, and interpreting data, along with problem solving, are crucial components of this course. The active participation of students during the seminars will certainly develop their methodological skills in the context of Pharmaceutical Sciences and Immunology.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 4
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT477-54
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
Introduction to Immunology and Innate Immunity History of immunology, importance and basic concepts Organs, cells, receptors and molecules that are fundamental to the functioning of the immune system Innate immunity and inflammation: The Complement System. The inflammatory reaction and the establishment of the adaptive immune response Adaptive immunity Antigen and Major Histocompatibility Complex receptors Organization and expression of lymphocyte receptor genes The Major Histocompatibility Complex and antigen presentation Development of T cells and B cells Activation, differentiation, and memory generation Antibody- and cell-mediated immunology The immune system in health and disease Allergies, hypersensitivities, and chronic inflammation Tolerance, autoimmunity and transplantation Infectious diseases and vaccines Neurodegenerative diseases: The case of Parkinson's Disease
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Objectives
Objectives
The student should: recognize the structure, organization, and function of the immune system. Know the different tissues, organs, cells, and molecules participating in the immune system, and how they interconnect in response to physiological and pathological stimuli. Understand and articulate between the innate and acquired immune system, as well as the regulation mechanisms between each one of these immune responses. The laboratory classes allow students to manipulate and analyze components of the immune system. Autonomy, organization, responsibility, and group cooperation are promoted in the laboratory.
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Teaching methodologies and assessment
Teaching methodologies and assessment
Whenever possible, digital materials to support master classes are made available, and forum discussion channels are open about their contents. Theoretical-practical and laboratory classes: Introduction to diagnostic/research techniques in immunology using demonstrative methods and active practice with guidance from the CBIOS professor and researchers. A seminar will be prepared with the students, with the presentation and discussion of a immune-ralated disease and the therapeutics associated. It is a "key" tool for developing critical thinking and understand the concepts presented in the theoretical classes.
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References
References
1. Janeway, C.A. et al, Immunobiology (2022), 10 th Ed., Garland Science. 2. Goldsby, R.A. et al.(2018), Kuby Immunology, 8th Ed., New York, W.H. Freeman & Company Eds. 3. Robert R. Rich MD. Et al., Clinical Immunology Principles and Practice (2019), Elsevier Limited. 3. Abbas, A.K., Lichtman, A.H.(2021), Cellular and Molecular Immunology, 10 th Ed., Elsevier/Saunders. 4. Arosa, F.A., Cardoso, E.M., Pacheco, F.C. (2014) Fundamentos de Imunologia (2º ed) Lidel.
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Office Hours
Office Hours
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Mobility
Mobility
No