Class Immunology

Immunology is a scientific branch that studies the immune system and its functions. In VM, immunology enables the prophylaxis and diagnosis of economically relevant diseases. The CU seeks to provide students with basic and current concepts of immunology that will allow them to understand the importance of the immune system in its various aspects and functions as a fundamental component for the balance and maintenance of good general animal condition. Virology is also addressed in this CU. The CU seeks to provide students with basic and current concepts of virology, including aspects related to taxonomy, biology, pathogenesis, infection cycles and viral diagnosis of different types of viruses with relevance to animal health, in order to establish appropriate control strategies. Special emphasis is given to the concepts of viral zoonoses and One Health, in order to control viral infections transmissible to humans through a global and multidisciplinary vision of health.

Not applicable

- Virology principles - Morphology, infection cycles and viral pathogenesis - Viruses with DNA, ssRNA(-), ssRNA(+) and dsRNA genomes - Viral zoonosis and the One Health concept - Immune system components - Innate and acquired immunity - Antigenic recognition - Major histocompatibility complex (MHC). Antigen presentation. Cellular immunity - T lymphocytes and NK cells - Humoral immunity - B lymphocytes e immunoglobulins - Types of immune response - primary and memory - Distinction between self and non-self - Vaccines - attenuated and inactivated. Good vaccination practices - Hypersensitivity reactions - Immune system evasion mechanisms - Virological and immunological diagnosis: Cell culture and in embryonated eggs, viral titer, hemmaglutination and hemmaglutination inhibition, PCR, microarrays and metagenomics, lateral flow immunocromatography, ELISA, crossmatching and blood typification - Regulation of the immune system, bacteriophages, immunodeficiency, immunotherapy and transplants

Expository and interactive classes, flipped classroom, jigsaw technique and its variants, concept maps.

- Flint, J., Racaniello, V.R., Rall, G. F., Hatziioannou, T., Skalka, A. M. (2020). Principles of Virology (5th ed.). USA: Wiley. - Malik, Y., Singh, R., Yadav, M. (2019). Recent Advances in Animal Virology. Singapore: Springer. - Tizard, I. (2018). Veterinary Immunology (10th ed.). USA: Elsevier. - MacLachlan, N., Dubovi, E. (2017). Fenner's Veterinary Virology (5th ed.). United Kingdom: Academic Press.