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Class Advanced Organic Chemistry

  • Presentation

    Presentation

    The UC intends to interpret and draw structures of organic molecules, correlating its name (common, IUPAC) with its structure. Correlate the structure and functionality of a compound with its family, its reactivity and its physical properties. Write, interpret and apply the mechanisms associated with the transformations of the main functional groups and interpret and assign structures of low complexity organic compounds, through the joint use of various structural elucidation methods (microanalysis, FT-IR, NMR, MS) applying these techniques. natural products and their applications in the areas of Health, Food and Environment.
  • Code

    Code

    ULHT2532-21534
  • Syllabus

    Syllabus

    1-Identification of Organic Compounds (HPLC); Spectroscopic and spectrometric techniques for structural analysis: NMR spectrometry techniques (1H, 13C). Infrared Spectroscopy (FT-IR). Mass spectrometry); 2- Addition reactions in alkenes and alkynes, addition-elimination in aldehydes, ketones, carboxylic acids and derivatives, electrophilic substitution in aromatics; 3- The carbonyl group: properties, synthesis and reactivity, Carboxylic acids and derivatives, properties, synthesis and reactivity. .Amines: properties, synthesis and reactivity. 4.Aromaticity. Aromatic electrophilic substitution; 5-Applications: natural products. Formation of biologically active pharmacological compounds from plants. Classifications of natural products. Natural products derived from amino acids. Alkaloids. Characterization of natural compounds: mass spectrometry, IR and NMR
  • Objectives

    Objectives

    Acquire a global perspective of the study of organic chemistry applied to plants and its interaction with other sciences. Acquire basic knowledge of natural product chemistry and scientific methods for application in the laboratory or industry in specific areas such as Pharmaceutical, Environment, Food and Health. Develop observation, reasoning and logic in problem solving and drawing conclusions. . Prepare the student in the knowledge and handling of extraction material in the laboratory following risk and safety rules. Allow students to distinguish natural molecules extracted from plants, microorganisms and synthetic molecules and to relate their structures to their reactivity and biological potential. Know how to extract and synthesize in the laboratory, purify and identify using traditional and modern techniques.
  • Teaching methodologies and assessment

    Teaching methodologies and assessment

    Implementation of extra classes online for student support with additional exercises for homework giving better understanding of the subject.
  • References

    References

    1- Solomons, T.W.G, Fryhle, C.B, Snyder S.A., "Organic Chemistry", 12 th Edition, Wiley, 2016. 2- K. P. Volhardt, N.E. Schore, W.E. "Organic Chemistry", Freeman and Company, 6Ed, 2010. 3- R. Morrison, R. Boyd, "Quimica Orgânica", Fundação Calouste Gulbenkian, 11 edição, 2011. 4-P. M. Dewick "Medicinal Natural Products" A Biosynthetic Approachg,, Wiley, Chichester, 2009  
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