Class Virology

This UC has as its main objective to give students a global view on the viruses that cause human pathologies, the structure of the viral particle, the organization, the type of genome, the clinical picture and the techniques / approaches used in the diagnosis, treatment and prevention of these infections.

Not applicable

1 - Introduction Historical landmarks Virus vs bacteria vs prion Structure and virion elements Environmental survival Taxonomy   2 - Genetics Genome organization Mutation and recombination   3 - Cell-virus interaction Cell and organism virus entry Viral pathogenesis mechanisms Viral gene expression and replication Viral particle assembly and release   4 - Host resistance to viral infection Viral tropism Innate immunity Adaptive immunity Pathological effects and viral infection patters Latent infections Viral oncogenesis   5 - Viral replication inhibition Viral inhibitors, targets and mechanisms   6 - Vaccination Vaccine groups National vaccination program   7 - Viral infections that induce human pathologies Structure, genome, clinical, symptomatology, transmission, pathogenesis, diagnosis techniques and prevention. Epidemiology

Active learning methodologies based on the resolution of practical problems, on the exposition by the students of some concepts addressed in laboratory classes and the use of observations/results obtained in the laboratory as a starting point for the discussion of more complex concepts/topics.

Madigan, M.T. et al.. (2019) Brock Biology of Microorganisms, 15th Ed., Upper Saddle River, Prentice-Hall International Editions, 2014 David M. Knipe, Peter M. Howley (2023), Fields Virology, 7th Ed., Lippincott Williams & Wilkins. Acheson, N H, (2011) Fundamentals of Molecular Virology, 2nd Ed, John Wiley & Sons, Inc Artigos científicos fornecidos pelo docente.