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Class Pharmaceutical Technology II

  • Presentation

    Presentation

    In a global perspective, Pharmaceutical Technology includes the scientific and technological aspects associated with different phases in which a drug is subject to the development and production of a pharmaceutical dosage form suitable for administration. Following the curricular units (CU) Galenic Pharmacy and Pharmaceutical Technology I, this CU is focused on the study of dosage forms for parenteral, ocular, nasal and auricular administration with emphasis on their production process and control quality assessment. This CU is of utmost importance for the practice of the pharmaceutical profession in the different intervention areas.
  • Code

    Code

    ULHT477-4115
  • Syllabus

    Syllabus

    Good manufacturing practices of sterile pharmaceutical forms. Sterilization and pyrogens. Aseptic technique. Formulations for parenteral administration. Injectable formulations of extemporaneous preparation. Freeze-drying in the pharmaceutical industry. Formulations for ocular administration. Formulations for nasal and auricular administration. Biopharmaceutical products. Nanotechnology. Industrial production of dosage forms for parenteral, ophtalmic, nasal and auricular administration.
  • Objectives

    Objectives

    This curricular unit aims to consolidate the expertise devoted to the development of formulation strategies for the parenteral, ocular, nasal, and auricular routes of administration with special emphasis on their production process and quality control tests.   After attending this curricular unit, the student will have acquired the following skills and competences: - understanding of the parenteral, ocular, nasal, and auricular routes of administration; - discernment of the various pharmaceutical forms for each route of administration; - production of pharmaceutical forms for each route of administration using the good manufacturing practices; - application of the relevant control quality tests for each route of administration; - discernment of the specificities of biopharmaceutical products; - understanding of the advantages and challenges of nanotechnology.
  • Teaching methodologies and assessment

    Teaching methodologies and assessment

    The UC has theoretical classes, practical classes and field research. The theoretical classes are magisterial encompassing the syllabus and the curricular unit's objectives, with stimulation of the active participation of students based on the use of interactive software. Practical classes deepen the contents taught in the theoretical component, using design thinking, flipped classroom and laboratory work. Based on problem-based active learning strategies, some practical classes will be dedicated to some professional careers for pharmacists, such as community pharmacy, hospital pharmacy and research. Students will also be challenged to idealize an industry and design the products to be marketed, using information technologies to present their work in a website format. Field research includes a study visit to the pharmaceutical industry and/or a seminar from pharmacists working in the industry, which are part of the Lusophone Week of Contact with the Pharmaceutical Profession.
  • References

    References

    Aulton, M. E., Taylor. K. M. G. (2021) Aulton’s Pharmaceutics: The design and manufacture of medicines (6th Edition). Elsevier. Allen, L., & Ansel, H. C. (2021). Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. (12th Edition). London: Wolters Kluwer Health. Nogueira Prista, L. et al. (2014) Tecnologia Farmacêutica (8a edição) Fundação Calouste Gulbenkian. Infarmed. (2008) Farmacopeia Portuguesa (IX Edição). Portugal.  
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