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Presentation
Presentation
This UC introduces the constitution, structure and funcion of the cell as a functional unit but also as part of multicelular organisms.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
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Code
Code
ULHT6580-944
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
The cell Cell theory Chemical composition Prokaryotic and eukaryotic cells Transport mechanisms Organelles and cellular structures ¿ structure/function relationship Biological membranes Nucleus ER, RER and Golgi complex Mitochondria Chloroplast Cytoskeleton ECM Intercellular communication and adhesion Cell-cell and cell-substrate adhesion Signalling pathways Genome Central dogma of Biology Different condensation states of chromatin Prokaryotic versus eukaryotic genome Gene Replication, transcription and translation DNA replication mechanism, replication fork, DNA polymerases Transcription mechanism, RNA polymerases Transcript processing Genetic code tRNAs and ribosome Polypeptide chain production Gene expression regulation Why regulate gene expression? Cell differentiation Cell cycle Mitosis and meiosis Cell cycle control Apoptosis
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Objectives
Objectives
After attending this CU, the student should know the structure and function of different cell types and their elements, and understand the basic mechanisms that allow cells to function as an independent unit or as part of a larger organism. The student should comprehend the relation between cell (and cellular elements) structure and function, as well as cellular regulation mechanisms. The student should also understand the mechanisms involved in the storage, usage and transmission of genetic information. The knowledge above mentioned is of extreme importance for the future understanding of cellular mechanisms involved in pharmacological action. The laboratory classes allow students to manipulate and analyse cells and their components. Autonomy, organization, responsibility, bibliography research and group cooperation are promoted in the laboratory and during the elaboration of an oral presentation.
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Teaching methodologies and assessment
Teaching methodologies and assessment
Active learning methodologies based on the resolution of practical problems, on the exposition by the students of some concepts addressed in laboratory classes and the use of observations/results obtained in the laboratory as a starting point for the discussion of more complex concepts/topics.
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References
References
Lodish, H et al. (2021), Molecular Cell Biology, 9th Ed, W. H. Freeman and Co. (Informação complementar online: http://bcs.whfreeman.com/lodish7e/#t_800911____) Reece, J. B, Urry, L. A., Cain, L. C., Wasserman, S. A., Minorsky, P. V., Jackson, R.B., (2016) Campbell Biology, 11th ed., Pearson Education, Inc. Campos, L.S. (2008); Entender a Bioquímica, 5ªed. Escolar Editora.
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Office Hours
Office Hours
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Mobility
Mobility
No
