Class Biochemistry II

Biochemistry II will allow students to understand how biological processes are organized and interdependent in networks of control. These systems allow the organism to maintain a relatively constant internal environment, respond quickly to external stimuli, grow and differentiate.

Not applicable

Introduction to metabolism (Metabolism, anabolism, catabolism). Source of energy and oxidation-reduction reactions. Aerobic metabolism Digestion and absorption of carbohydrates. Glycolysis. Fermentations associated with glycolysis. Glycogen breakdown and Glycogen synthesis Gluconeogenesis. Cycle of pentose phosphates. Cycle of Carboxylic Acids. Mitochondria and oxidative metabolism. Reactive oxygen species. Photosynthesis Phase of photosynthesis The dark phase Lipid metabolism Digestion, absorption and transport. Beta-oxidation of fatty acids. Biosynthesis of fatty acids. Cholesterol metabolism Metabolism of amino acids Digestion of proteins Transamination and deamination of amino acids Urea cycle. Catabolism of ketoacids. Biosynthesis of amino acids. Purine metabolism Metabolic Interrelationships Fasting-feeding cycle Nutritional and hormonal states

In the Biochemistry 2 course, innovative pedagogical approaches will be applied to enhance the teaching and learning process. Among these approaches, flipped learning stands out, where students prepare presentations on the program content and, at the end, evaluate their peers and conduct a self-assessment to stimulate knowledge and self-criticism. The course also includes a fieldwork component in the form of a seminar on Biochemistry, featuring an external guest speaker. This event will provide a practical and updated perspective on relevant topics in the discipline, deepening the theoretical and practical concepts discussed in class. Participation in the seminar will allow students to connect theory with real-world application, offering them an additional perspective on the impact and innovations in the field of Biochemistry.

Voet, D. & Voet. J.G. Biochemistry, (4th Ed). New York: John Wiley & Sons. 2010 Halpern M, Freire A, Quintas A. Bioquímica Organização Molecular da Vida. Lidel 2008 Berg, J.M. et al. Biochemistry (7th Ed). New York: Freeman and Company. 2010 Devlin T. Textbook of biochemistry; with clinical correlations. (7th Ed). Blucher. 2011 Weil, J.H. Bioquímica Geral (2ª Ed). Lisboa: Fundação Calouste Gulbenkian. 2000