Class General Biochemistry

The Biochemistry curricular unit aims to introduce and deepen several general and fundamental concepts of this scientific area, allowing an interconnection with other specific areas, namely, Biomedicine, Engineering, Microbiology among others. The practice component allows preparation in the various techniques used in Biochemistry granted as fundamental tools in the preparation for future performance in several areas, specifically, in the area of research and in the area of Biotechnology and Biomedicine in general.

Not applicable

1-Introduction to Biochemistry. Water chemistry. 2-Physico-chemical properties of amino acids 3-Proteins and their characterization:    3.1-Structural aspects and function    3.2-Hemproteins: structure-function relationship in biological macromolecules: transport of oxygen and carbon dioxide (hemoglobin and myoglobin)    3.3-Enzymes: general concepts; enzymatic kinetics (Michaelis-Menten model) 4-Carbohydrates: monosaccharides and polysaccharides; glycoproteins. 5-Lipids: constitution and function. 6-Nucleic acids (RNA and DNA): structure and function.    6.1-The flow of genetic information: from the gene to the protein.    6.2-Recombinant DNA technology 7-Introduction to bioenergetics.    7.1-Glycolysis and fermentation, citric acid cycle.    7.2-Oxidative phosphorylation: electron transport chain and ATP synthesis.

Develop teaching strategies using practical examples arising from real data for critical analysis by students. Develop and encourage critical thinking.

Nelson, D.L., & Cox, M.M. (2008) LEHNINGER PRINCIPLES OF BIOCHEMISTRY W.H. Freeman and Company, San Francisco, 5th ed. Voet, D., Voet, J.G. & Pratt, C.W. (2008) PRINCIPLES OF BIOCHEMISTRY, John Wiley & Sons, Inc., New York, 3rd ed. Lubert Stryer, W. H. (2007) BIOCHEMISTRY Freeman and Company, San Francisco. 6th Ed. Quintas A, Freire AP, Halpern MJ. (2008) BIOQUÍMICA - ORGANIZAÇÃO MOLECULAR DA VIDA , LIDEL.