Class Biochemistry II

Biochemistry II focuses on the study and understanding of the main diagnostic techniques used in clinical biochemistry. It addresses the study of biochemistry as a fundamental component for the interpretation of health status and disease.

Not applicable

1) Diabetes biochemistry, laboratory evaluation 2) Non-protein nitrogen. Laboratory evaluation of urea, uric acid. 3) Hydroelectrolytic balance a) Changes in the water balance b) Electrolytes: Sodium; Potassium; Chloride. Methods of determination 4) Acid-base balance a) Importance of buffer systems in regulating the pH of physiological liquids. Methods of evaluation of acid-base balance b) Respiratory mechanism of acid-base balance regulation c) Renal compensation mechanisms 5) Renal function a) The importance of renal function in electrolyte balance b) Methods of evaluation of renal function and creatinine 6) Hepatic function a) Laboratory biochemical evaluation of liver function 7) Endocrinology a) Mechanism of action of hormones and hormone receptors b) Thyroid hormones c) Thyroid dysfunctions d) Analytical methods 8) Exocrine gastric, intestinal and pancreatic function and laboratory evaluation

Inverse learning, the students prepare the lessons under the guidance of the teacher, at the final the students evaluate their peers and make a self-evaluation, to stimulate knowledge and self-criticism.  Availability of the teacher to monitor the preparation of lessons and organisation of content. Knowledge progression tests throughout the semester are prepared at home through the learning platform.

Marshall, W. J., Bougut, S. K., Clinical Chemistry, 7th edition, St. Louis, C.V. Mosby Company, 2012 Burtis, C., Ashwood, E., Tietz Fundamentals of Clinical Chemistry, 6th edition, Philadelphia, W.B.Saunders Company. 2008 Kaplan, L. A. et al., Clinical Chemistry: theory, analysis, correlation, 4th edition, St. Louis, C.V. Mosby Company. 2003 Halpern M, Freire A, Quintas A. Bioquímica Organização Molecular da Vida. Lidel. 2008 Berg, J.M. et al. Biochemistry (7th Ed). New York: Freeman and Company. 2010 Devlin T. Textbook of Biochemistry with clinical correlations. (7th Ed). Blucher. 2011