-
Presentation
Presentation
Biochemistry is an interdisciplinary science that involves an interrelationship between basic disciplines such as chemistry and biology. Biochemistry has a very important role in several areas, particularly in the Food and Pharmaceutical Industries, in the Environment, in the various aspects of Toxicology and in the Health area.
-
Class from course
Class from course
-
Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 4
-
Year | Nature | Language
Year | Nature | Language
1 | Mandatory | Português
-
Code
Code
ULHT477-33
-
Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
-
Professional Internship
Professional Internship
Não
-
Syllabus
Syllabus
Introduction to Biochemistry Biochemistry and its objectives. Origin of life The water Water properties Acids, bases and buffers Amino acids and proteins The peptide bond Structural levels of proteins Active and regulatory centers Myoglobin and hemoglobin The enzymes Lipids Structure of lipids Definition and classification of lipids Biological membranes Carbohydrates Definition and vocabulary. Ranking. Introduction to bioenergetics The principles of thermodynamics. The free energy of Gibbs. ATP - production and hydrolysis Biological information Composition and primary structure of nucleic acids Three-dimensional structure of DNA Three-dimensional structure of the various RNAs
-
Objectives
Objectives
The discipline of Biochemistry I aims to define the concept of biochemical reaction, introduce students to the different actors of biochemistry (water and biomolecules) and introduce the great biochemical functions such as the functioning of enzymes, bioenergetics and biological information. Students should know and understand the structure and properties of the major classes of biomolecules (carbohydrates, lipids, amino acids and proteins and nucleic acids) and their interactions with the solvent water. Capacity in basic methodology in the scope of Biochemistry (realization of reagent solutions, colorimetry, liquid chromatography, solid support chromatography, calibrations, spectrophotometry). At the conclusion of the course, students should master the bases that will allow them to approach the curricular unit of Biochemistry II.
-
Teaching methodologies and assessment
Teaching methodologies and assessment
Knowledge progression tests throughout the semester were carried out at home through the learning platform. Pedagogical games in the classroom capture students' attention and motivate learning. Fieldwork” teaching through a seminar on the subject of biochemistry as a basic science for understanding biological phenomena.
-
References
References
Voet, D. & Voet. J.G. Biochemistry, (4th Ed). New York: John Wiley & Sons. 2010 Halpern M, Freire A, Quintas A. Bioquímica Organização Molecular da Vida. Lidel. 2008 Berg, J.M. et al. Biochemistry (7th Ed). New York: Freeman and Company. 2010 Devlin T. Textbook of biochemistry ; with clinical correlations. (7th Ed). Blucher. 2011 Weil, J.H. Bioquímica Geral (2ª Ed). Lisboa: Fundação Calouste Gulbenkian. 2000
-
Office Hours
Office Hours
-
Mobility
Mobility
No
