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Class General Microbiology

  • Presentation

    Presentation

    The UC General Microbiology addresses the study of Biology, diversity, and the relationship of microorganisms, in particular bacteria, with their hosts. The UC is a first approach to the defined areas, which will be consolidated during the course, through the UCs Genetics, Pharmacology, Virology and Immunology. The Pharmacist is often the first contact of users with health professionals, thus the UC introduces the study of infectious diseases sought in Public Health to alert/prepare students for their responsibilities as professionals. The knowledge acquired by students in this UC form an essential basis for conventional Pharmacist working areas, including infection control, food and environmental microbiology as well as other innovative areas such as new therapeutics and new foods. 
  • Code

    Code

    ULHT477-3875
  • Syllabus

    Syllabus

    1. Prokaryotic cells I: structure and functional anatomy   2. Prokaryotic cells II: physiology 2.1 Nutrition and growth 2.2 Metabolism   3. Virus 3.1 Bacteriophages   4. Microbial genetics 4.1 Replication, transcription and translation 4.2 Mutations and genetic material transfer    5. Asepsis and antimicrobial agents 5.1 Physical and chemical agents 5.2 Mechanisms of action of antibiotics and bacterial resistance 5.3 Antibiotics: spectrum of action and therapeutic indications   6. Bacteria/host interactions 6.1 Concepts of colonization, infection and disease 6.2 Microbial virulence factors 6.3 Host defense mechanisms   7. Clinical Microbiology - pathogenesis and laboratory diagnosis of microbial infections 7.1 Systemic infections 7.2 Gastrointestinal infections 7.3 Genito-urinary infections 7.4 Respiratory infections 7.5 Tuberculosis 7.6 Healthcare-associated infections
  • Objectives

    Objectives

    The UC intends to teach the basic knowledge about infectiology, which will later be consolidated in the UCs Genetics, Pharmacology, Virology, and Immunology enabling the dialogue of the Pharmaceutical Sciences professional with clinicians and users. It is also intended to stimulate the scientific curiosity of students to open horizons to possible areas of scientific investigation. To achieve these goals, the skills and competences to be developed by students include: a) deepening knowledge about prokaryotic cells; b) understanding the mechanisms of action and resistance to antibiotics; c) knowing the microorganism/host relationship; d) understanding the mechanisms of pathogenesis, treatment and epidemiology of bacterial infectious diseases; e) learning the safety standards of Microbiology laboratories and microbiological techniques for the study of biological samples.
  • Teaching methodologies and assessment

    Teaching methodologies and assessment

    Teaching methodology:   Theoretical classes: expository and demonstrative methods, with active participation of students by encouraging discussion through debates, presentation of oral works, etc.   Laboratory classes: expository, demonstrative and practical methods based on the active method with teacher guidance.   Teaching in the "Fieldwork" format, through study visits and/or seminars with external guests, as part of Lusophone Week: Contact with the Pharmaceutical Profession (Pharma Week).   As innovative methodologies to support the teaching-learning process, the UC uses multiple active teaching strategies, as it is the case of online platforms to support active teaching (Kahoot, Mentimeter, etc.) and tools available on Moodle.
  • References

    References

    - Wanda F. Canas Ferreira , João Carlos F. de Sousa, Nelson Lima. 2010. Microbiologia. Edições Lidel  - Helena Barroso , António Meliço-Silveira, Nuno Taveira. 2014. Microbiologia Médica, Volume 1. Edições Lidel - Helena Barroso , Anónio Meliço-Silveira, Nuno Taveira. 2013. Microbiologia Médica, Volume 2. Edições Lidel - Prescott, L.M. et al. 2002. Microbiology, 5th Ed Boston, MacGraw Hill - Bailey e Scotts. Diagnostic Microbiology, 2002, 11a edição, Betty Forbes, Daniel Sahm, Alice Weissfeld, Mosby  
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