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Presentation
Presentation
Knowledge about disease mechanisms are crucial for training in human health, essential for structuring deductive thinking related to the analysis of the mechanisms of alteration of the normal physiological functions within the individual as a whole. This mechanistic view stems from the identification of the signs and symptoms that characterize the different periods of the disease's evolution, using the differential means of diagnosis (laboratorial, functional, imagiological) available. This presupposes an in-depth knowledge of the integrated physiology on which this practice is developed.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 5
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT477-3905
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
Disease as a maladaptive response; genetics and the environment: susceptibility and multifactorial diseases. Neoplasia and genetic mutations; oncogenes and suppressor genes; Primary and secondary immunodeficiencies. inflammation, regeneration, repair and healing. Infectious disease: responses of the immune system to infectious agents; sepsis. Hematological disease: coagulation factors, figured elements of the blood; Endocrine disorders and current morbility expression - e.g. diabetes Heart failure, ischemic heart disease, high blood pressure and shock Restrictive / obstructive pulmonary disease - COPD, emphysema, pneumoconiosis and asthma Glomerulonephritis, renal tubular diseases and kidney failure; acid-base disorders. Renal disfunction and metabolic impact ; Disease of the gastrointestinal tract to inflammatory bowel disease. Liver and bile duct disease. Metabolic disease - inate and acquired (importance of obesity) Neurodegenerative diseases and aging. Psiquiatric and behavioral diseases.
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Objectives
Objectives
To learn about the general mechanisms of disease including the understanding of disease as a maladaptive response to internal and external changes. To understand the role of genetics and environment in disease. To learn about the physiological mechanisms related to the pathology of several organs and systems. To relate learnt concepts with biomedical engineering and its role in prevention, diagnosis, and treatment of disease, and in rehabilitation as well.
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Teaching methodologies and assessment
Teaching methodologies and assessment
this curricular unit (CU) uses various active learning strategies such as the virtual human body from Anatomage, among others, to stimulate logical deductive reasoning; this CU also includes "field work" by study visits and/or seminars with external lecturers, inserted in the Lusofona Week of Contact with Pharmaceutical Professions
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References
References
¿Pathophysiology of Disease ¿ An Introduction to Clinical Medicine¿, Stephen J. McPhee e William F. Ganong (Eds), Lange Medical Books/McGraw-Hill. 2018 ¿Kumar & Clark¿s Clinical Medicine¿, Parveen Kumar and Michael Clark (Eds), Saunders/Elsevier, 2018 ¿Fisiopatologia - Fundamentos e Aplicações (2ª Edição)¿, Anabela Mota Pinto (Ed), Lidel. 2016
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Office Hours
Office Hours
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Mobility
Mobility
No
