Class Pharmaceutical Technology III

This CU aims to conclude an area of integrated development initiated with Pharmaceutical Technology I. In this context, one of its main obejectives is to consolidate the areas of knowledge devoted to developing formulation strategies for the topical, transdermal, rectal and vaginal route. The main aspects of stability preservation will also be addressed, as well as the reology and viscosity of such formulations.

Not applicable

Transdermal and topical  drug delivery: Modulating factors of the skin delivery route Advantages and disadvantages   Semi-solid formulations:   Preparation methods Packaging Quality control   Transdermal delivery systems: Types of TDS Formulation strategies and production systems Quality control   Rectal formulations: Rectal delivery route Preparation methods Packaging Quality control   Vaginal formulations: Vaginal delivery route Preparation methods Packaging Quality control   Reology: Newtonian and non-newtonian fluids Impact of reology in the bioavailability of drugs   Good Manufacturing Practices   Stability: Factors that affect stability Instability pathways Oxidation and antioxidants Methods to establish stability and expiry date

Flipped classrooms, where traditional lectures are replaced with interactive online content and face-to-face discussions, promoting active learning and deeper understanding. Project-based learning, which allows students to apply theoretical knowledge to challenges in the professional world, promoting critical thinking and problem-solving skills. Quizzes with Kahoot or similar software. During field work, students come into contact with professional activity through a visit to a pharmaceutical industry production unit.

  1. Taylor, K.M.G., Aulton, M. E., (2021). Pharmaceutics - The Science of Dosage Forms Design, 6th Ed., Edinburgh, Churchill Livingstone Lachman, L. Lieberman, H.A., Kanig, J.L.. (2001). Teoria e Pratica na Indústria Farmacêutica, vol. II, Lisboa, Fundação Calouste Gulbenkian Prista, L. N., Alves, A.C., Morgado, R.,(2006). Tecnologia Farmacêutica, vol. II, 4ª Edição, Lisboa, Fundação Calouste Gulbenkian Prista, L. N. Alves, A.C., Morgado, R., (2008). Tecnologia Farmacêutica, vol. III, 4ª Edição, Lisboa, Fundação Calouste Gulbenkian Hillert, A.M. et al., (2001) Drug delivery and targeting for pharmacists and pharmaceutical scientists, London, Taylor & Francis