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Presentation
Presentation
Toxicology is presented as a multidiciplinary science for poisoning diagnose ante and post-mortem, but also for developement and analisys of toxicological studies, safety values determinatios and related environmental impact evaluation, considered therefores as indispensible for clinicians, particulaly to veterinary health public professionals , ensuring food safetu and feed quality to animals.
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Class from course
Class from course
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Degree | Semesters | ECTS
Degree | Semesters | ECTS
Bachelor; Master Degree | Semestral | 3.5
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Year | Nature | Language
Year | Nature | Language
3 | Mandatory | Português
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Code
Code
ULHT478-7565
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Prerequisites and corequisites
Prerequisites and corequisites
Not applicable
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Professional Internship
Professional Internship
Não
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Syllabus
Syllabus
1- General Toxicology 1.1 - toxic agents, Poisening and toxic´s classification 2- Exposure 2.1 - Acute, sub-acute, sub-chronic and chronic, administration routs constraints 3- Mechanisms of action 3.1- local and systemic effects able to modify reversible and not reversible effects 4- IToxic agenst Interactions 4.1 - Aditiv, synergic, potentiate and antagonic effects, Bioavailability and antagonic receptors 5- Food Tocicology 5.1 - Toxci agents in food, residues, monitoring, ilegal substances. Food safety 6- Tocicological assays 6.1 - Protocols, international guidelines, risk assessment and safe limits determination 7- Ecotoxicology 7.1 - Cinetic and dinamic in the envarionment, biomarkers, endocrin disruptors, monitoring 8- Clinical Toxicology 8.1- Animal poisening; diagnosis, evaluation and treatment 9- Analytical Toxicology 9.1 Laboratory methods for analyusis in different matrixes
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Objectives
Objectives
1- General Toxicology 1.1 - toxic agents, Poisening and toxic´s classification 2- Exposure 2.1 - Acute, sub-acute, sub-chronic and chronic, administration routs constraints 3- Mechanisms of action 3.1- local and systemic effects able to modify reversible and not reversible effects 4- IToxic agenst Interactions 4.1 - Aditiv, synergic, potentiate and antagonic effects, Bioavailability and antagonic receptors 5- Food Tocicology 5.1 - Toxci agents in food, residues, monitoring, ilegal substances. Food safety 6- Tocicological assays 6.1 - Protocols, international guidelines, risk assessment and safe limits determination 7- Ecotoxicology 7.1 - Cinetic and dinamic in the envarionment, biomarkers, endocrin disruptors, monitoring 8- Clinical Toxicology 8.1- Animal poisening; diagnosis, evaluation and treatment 9- Analytical Toxicology 9.1 Laboratory methods for analyusis in different matrixes
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Teaching methodologies and assessment
Teaching methodologies and assessment
Active learning/problem-based learning activities, quizzes, clinical cases, and exercises are implemented in order to stimulate students' enthusiasm for the subject and their involvement in classes. These approaches, in addition to involving students in their learning, also help in the application and consolidation of knowledge and syllabus content, and the classroom environment is more engaging and productive. Formative assessments are used to support teaching and learning in the classroom. The feedback facilitated by formative assessments enables teachers to adapt their instruction to the needs of students, taking into account their individual characteristics, difficulties, and gaps, and provide feedback to students; students can use such feedback to self-regulate their study and steer their own learning processes directly.
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References
References
Ramesh C. Gupta, 2012 Veterinary Toxicology . Basic and Clinical Principles , Academic Press, San Diego.ISBN: 978-0-12-385926-6 Curtis D. Klaassen, 2013, Casarett and Doulls Toxicology - The Basic Science of Poisons , 8th ed. , McGraw-Hill. New York ISBN 978-0-07-176923-5 Repetto M , 2009 , Toxicologia Fundamental , 4ª Ed., Ed. Diaz de Santos, Madrid ISBN 978-84-7978-898-8 Robert J. Flanagan et al., 2007, Fundamentals of analytical toxicology, John Wiley & Sons ISBN 978-0-470-31934-5. Walker, C.H., Hopkins, S.P., Sibly, R.M. & Peakall, D.R. (2012). Principles of Ecotoxicology . (4ª Ed.). CRC Press. ISBN 978-1-43-986266-7
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Office Hours
Office Hours
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Mobility
Mobility
No