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Class Redox Biochemistry and Bioelectrochemistry

  • Presentation

    Presentation

    The Redox Biochemistry and Bioelectrochemistry course explores the fundamental principles of oxidation-reduction reactions in biological systems and their electrochemical applications. This CU integrates concepts from biochemistry and electrochemistry to understand how oxidation-reduction reactions influence cellular processes and how these reactions can be applied in innovative technologies.
  • Code

    Code

    ULHT6942-25997
  • Syllabus

    Syllabus

    Concept of redox potential. Oxidation and reduction reactions. Oxidizers and reducers. Electron transfer. Homogeneous and heterogeneous, direct and mediated redox reactions. Redox energy balance. Spontaneity and reversibility of reactions. Biological electron. Free radicals and oxidative stress. Signaling and redox regulation and redox enzymes. Electrochemical methods and techniques, potentiometry and interfacial electrochemistry. Solution and immobilized systems. Electrochemical cell. Electrodes and conditions. Cyclic and pulsed voltammetry; chronoamperometry. Examples of coupled techniques (e.g. spectroelectrochemistry, electrochemical scanning microscopy, quartz crystal electrochemical microbalance). Practical applications in biochemistry-mechanisms, catalysis, microbiological corrosion, biofuel cells (enzymatic and microbiological).
  • Objectives

    Objectives

    The course of Redox Biochemistry and Bioelectrochemistry has as objectives that students know the fundamental concepts of redox biochemistry, namely reduction and oxidation reactions, electron transfer, concepts of oxidants and reducers, free radicals and oxidative stress, spontaneity of reactions, signaling and redox regulation and electrocatalysis. Students will also learn the theoretical and practical concepts necessary for the concrete study of biochemical redox phenomena through bioelectrochemical techniques. Recognize the most suitable techniques for practical application depending on the system or objective under study and develop skills in the area for current and emerging applications.
  • Teaching methodologies and assessment

    Teaching methodologies and assessment

    Theoretical classes (T) are face-to-face, privileging direct contact with students. Interactive lectures and Problem-Based Learning classes are planned. In practical classes (PL) students will contact with some examples of experimental techniques, analyze results and apply the knowledge acquired in the theoretical classes. Case studies will also be carried out.
  • References

    References

    1. Banerjee, R, Becker, D. F., Dickman, M. B., Gladyshev, V. N., Ragsdale, S. W. (Eds), (2008) Redox Biochemistry, John Wiley & Sons. 2. Brett, C. and Brett, A. M. O. (1993), ELECTROCHEMISTRY-Principles, Methods, and Applications, Oxford Uni. Press. 3. Bartlett, P. N. (Ed) (2008) Bioelectrochemistry-Fundamentals, Experimental Techniques and Applications, John Wiley&Sons. 4. Selected papers related with the contents and techniques will be made available.  
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